Writer Beware just posted on Facebook a blog post from io9 (keeping up?) about classic science-fiction and fantasy novels that have been massively, crushingly rejected multiple times. I shouldn't indulge myself in lists like this, because even though these great works were rejected, it doesn't necessarily follow that MY work, which has also been rejected, is also great.
Still, there is comfort in musing that rejection per se does not necessarily mean my work sucks. It may suck, of course, but then it may not.
The inner life of a writer is a minefield. A veritable minefield. And people wonder why so many writers take to drink.